Active substance: Dutasteride
Active life: ~5–6 days
Detection time: Approximately 4 to 6 weeks, depending on dosage and individual metabolism.

Dutasteride is a 5-alpha reductase inhibitor used primarily to treat benign prostatic hyperplasia (BPH) and, in some cases, male pattern baldness. It works by inhibiting both type I and type II forms of the 5-alpha reductase enzyme, leading to a more significant reduction in dihydrotestosterone (DHT) levels compared to Finasteride. By reducing DHT, Dutasteride helps shrink the prostate and may improve urinary symptoms related to BPH. It also helps in preventing hair loss by maintaining the hair follicles in individuals with androgenic alopecia.

How to use:
Dutasteride is typically taken once daily, with or without food, for the management of hair loss or prostate enlargement.

Common dosage:
0.5 mg per day for BPH and male pattern baldness.

Important considerations:
Side effects may include reduced libido, erectile dysfunction, and changes in ejaculation, similar to those seen with Finasteride. These side effects may be reversible upon discontinuation.

Long-term use requires monitoring for potential prostate-related issues, including prostate cancer, though the risk is low. Dutasteride has a longer half-life than Finasteride, meaning it stays in the body longer and may take more time to clear.

Not recommended for use in women or children, especially during pregnancy, as it may cause birth defects in male fetuses. Caution is also advised for individuals with liver or kidney issues.

Dutasteride is primarily used to manage DHT-related conditions, with its main applications being the treatment of hair loss and BPH.